Hippocampus anatomy sulcus coronal high resolution t1 mri

Post-mortem MRI and histopathological analysis suggested that the hypointense HT2Hs on FLAIR were cavities filled with cerebrospinal fluid. FLAIR hypointense HT2Hs were all located in the vestigial sulcus of the hippocampus, FLAIR hyperintense HT2Hs in the hippocampal sulcus or the gray matter. Of all HT2Hs, 94% was hypointense and 6% hyperintense on FLAIR. All HT2Hs detected on the T2 sequence were hypointense on T1 weighted images. HT2Hs were present in 97% of the subjects (median number per person 10 range 0РІР‚вЂњ20). HT2Hs identified in these slices were subjected to histopathological analysis. In addition, four formalin-fixed brain slices from two subjects were scanned overnight. Also, the location and number of the HT2Hs were assessed. MR signal characteristics of the HT2Hs were assessed on these images by two raters. They all underwent 7Р’В Tesla MRI, including a T1, T2, and FLAIR image. We also performed an explorative post-mortem study to examine the histology of HT2Hs.Р”Р‡ifty-eight persons without a history of invalidating neurological or psychiatric disease (mean age 64Р’В Р’В±Р’В 8Р’В years range 43РІР‚вЂњ78Р’В years), recruited through their general practitioners, were included in this study.

In this study we aimed to describe these HT2Hs in more detail using high resolution 7Р’В Tesla MR imaging, addressing 1) the MR signal characteristics of HT2Hs, 2) their occurrence frequency, 3) their location within the hippocampus, and 4) their relation with age. There is uncertainty about their etiology and clinical significance. Hippocampal focal T2 hyperintensities (HT2Hs), also referred to as hippocampal sulcal cavities, are a common finding on Magnetic Resonance (MR) images.

Hippocampus anatomy sulcus coronal high resolution t1 mri